A party spokesman said that the nomination has been made by PPP Chairman Bilawal Bhutto Zardari.
Muttahida Qaumi Movement-Pakistan (MQM-P) took the third position with 16 seats in the provincial assembly.
On Saturday, Muhammad Zubair Umar resigned from his position as Sindh Governor.
Zubair, who is brother of Pakistan Tehreek-e-Insaf (PTI) leader Asad Umar, had been appointed the 32nd Governor of Sindh in February 2017.
According to Muhammad Zubair , he has sent his resignation to President of Pakistan Mamnoon Hussain.
During the former PML-N government, Muhammad Zubair also served as chairman of the Privatisation Commission of Pakistan from 2013 to 2017.